ceesdekker.net - An Overview

Halfway as a result of his occupation, Cees Dekker reinvented himself. After several years of hardcore physics, he shifted his focus to ‘nanobiology’ with the turn on the millennium. A term he coined himself, being a make any difference of truth.

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules

‘It was basically a make any difference of selecting up a reserve on cell biology and beginning to browse. I had come from a globe of ultra-superior vacuums, cryostats and quantum phenomena, and now I used to be Operating at place temperature with molecular biology kits.

A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola

This yielded a breakthrough. Inside of just a few months, we were being able to measure transport by way of somebody one-walled carbon nanotube. Based on minimal-temperature experiments by an excellent PhD university student in my team, Sander Tans (now a valued colleague and professor at Delft College of Technologies with the Energetic investigation lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes ended up legitimate quantum wires with pretty lengthy (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.

Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van ceesdekker.net de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

Length control of particular person carbon nanotubes by nanostructuring Using the scanning tunneling microscope

2000, discovery that nanotubes can carry amazing big present densities; fixed the controversial concern of electronic transportation through DNA molecules by measurements of insulating behavior at The only molecule stage; and demonstration of an AFM approach for one-molecule manipulation of nanotubes

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‘The fantastically subtle way by which elements in mother nature purpose under no circumstances ceases to amaze me. If we fix the puzzle of how existence came into being, I hope that my amazement for the complexity of development may have increased and with it my awe for the greatness of your Creator.’

Considering that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from reports of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Extra not long ago his analysis has centered on learning chromatin composition and cell division with microbes on chip, even though he is also aiming to in the end Establish synthetic cells from The underside up.

Cees Dekker is Distinguished University Professor at TU Delft. Educated as being a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes inside the nineties. Given that 2000, he moved to solitary-molecule biophysics and nanobiology. His existing analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in particular SMC motor protein; and (iii) developing a residing synthetic cell from lifeless molecules. Dekker is definitely an elected member from the KNAW and fellow towards the APS as well as the IOP.

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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim with the pore is highlighted in crimson, in addition to a 3D rendering on the movement in the DNA rod is exhibited.